Pioglitazone Improves Whole-Body Aerobic Capacity in MetS

Pioglitazone Improves Whole-Body Aerobic Capacity in MetS

For adults with metabolic syndrome (MetS), pioglitazone treatment improves whole-body aerobic capacity, according to a study published online Dec. 12 in the Journal of Diabetes Investigation.

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Cancer drugs may remain approved despite lack of benefit

Cancer drugs may remain approved despite lack of benefit

In the United States, cancer drugs are sometimes approved through sped-up processes - and they often stay approved even if later studies show them to be inferior to other options or even worse than doing nothing, a new study found.

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POLARIS-2: Voxilaprevir safe, effective with Epclusa in multiple HCV genotypes

POLARIS-2: Voxilaprevir safe, effective with Epclusa in multiple HCV genotypes

BOSTON — A novel pangenotypic protease inhibitor, voxilaprevir, yielded encouraging outcomes when administered with Epclusa, regardless of HCV genotype or cirrhosis status, but remained non-inferior to the combination direct-acting antiviral, according to findings presented at The Liver Meeting 2016.

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Snippet: Role of carvedilol in mild to moderate hypertensive patients

Snippet: Role of carvedilol in mild to moderate hypertensive patients

Studies have confirmed the effectiveness of the drug carvedilol as monotherapy in managing patients with mild to moderate hypertension.

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EUCLID: Ticagrelor not superior to clopidogrel for CV event reduction in patients with PAD

EUCLID: Ticagrelor not superior to clopidogrel for CV event reduction in patients with PAD

NEW ORLEANS — Ticagrelor was not shown to be superior for reducing CV events in patients with symptomatic peripheral artery disease, according to a presentation at the American Heart Association Scientific Sessions.

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Research Article: Tacrolimus for Remission Induction and Maintenance Therapy in Patients with Ulcerative Colitis: A Retrospective Evaluation Study

Research Article: Tacrolimus for Remission Induction and Maintenance Therapy in Patients with Ulcerative Colitis: A Retrospective Evaluation Study

In this study: The clinical features and relapse rates were compared in the two groups. Maintenance therapy in the TAC group included TAC alone, azathioprine (AZA) alone, and TAC plus

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Daclizumab approved (ZinbrytaTM) for relapsing forms of multiple sclerosis

Daclizumab approved (ZinbrytaTM) for relapsing forms of multiple sclerosis

Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease of the central nervous system that disrupts the brains ability to communicate with various parts of the body.

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Society and superbugs: Losing ‘one of the most serious infections disease threats of our time’

Society and superbugs: Losing ‘one of the most serious infections disease threats of our time’

"Superbugs" are strains of bacteria that have become resistant to antibiotics, and they have been gaining strength and shifting the tide in their favor.

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FDA grants ezutromid rare pediatric disease status for Duchene muscular dystrophy

FDA grants ezutromid rare pediatric disease status for Duchene muscular dystrophy

The FDA has granted a rare pediatric disease designation to Summit Therapeutics for ezutromid in the treatment of Duchenne muscular dystrophy, according to a company press release.

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Snippet: Twin pregnancies complicated by preterm birth

Snippet: Twin pregnancies complicated by preterm birth

Administration of a complete course of antenatal corticosteroids 1-7 days before birth in twin pregnancies is associated with a clinically significant decrease in neonatal mortality, short-term respiratory morbidity and severe neurologic injury that is similar in magnitude to that observed among singletons.

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