Elevated cardiac troponin levels in patients with diabetes mellitus indicate the presence of coronary artery diseases.

Cardiac-specific troponin (cTn) chronically elevate in response to cardiovascular co-morbidities, it is an important prognostic tool in the absence of unstable coronary syndromes.

Do the diabetic patients with coronary artery diseases (CAD) have any difference in the troponin levels compared to the diabetic patients with normal coronary arteries? It was addressed in the present study.

  • Diabetics with CAD (12.0 pg/mL) had higher levels of troponin than diabetics without CAD (7.0 pg/mL).
  • Patients with CAD had higher concentrations of total cholesterol and LDL cholesterol.
  • However the parameters like brain natriuretic peptide (BNP) and oxidative stress variables (myeloperoxidase, nitrotyrosine and oxidized LDL) did not have much difference.

The elevation of cardiac troponin levels in diabetic patients with multiple associated cardiovascular risk factors indicates the presence of coronary artery diseases.

Citation
Segre et al. Troponin in diabetic patients with and without chronic coronary artery disease. Cardiovascular Disorders. 2015, 15:72.

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