Biprosthetic valves despite higher structural failure rate may be best suited especially in child bearing age females and the late complications in survivors were primarily anticoagulant related.

  • Retrospective analysis of female patients who underwent mechanical heart valve replacement was done to assess the long term outcome in indigent patients afflicted with rheumatic valvular disease.
  • The operative mortality was about 11.5% and morbidity was of 7.7%.

Observations:

  • 10-year freedom from bleeding and thromboembolism was 70.0% and survival 86.0% ( 13% of late deaths).
  • Linearized rate for bleeding was 4.58 and thromboembolism 1.52.
  • Thus, late complications in survivors were primarily anticoagulant related occurring predominantly in child bearing age females especially during pregnancy.
  • There was no structural valve deterioration, endocarditis or reoperation during the study period.

The study concluded that the biprosthetic valves despite higher structural failure rate may be best suited especially in child bearing age females still desirous of childbirth to decrease valve related complications.

Citation
Nwiloh et al. Experience with Prosthetic Valve Replacement in Indigents with Rheumatic Heart Disease in Nigeria: 10-Year Follow-Up. World Journal of Cardiovascular Surgery. 2015,05,75-81.

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